Hemp Investor
Helping you find the best Cannabis products, news, media and Investing opportunities

The effect of cannabis edibles on driving and blood THC | Journal of Cannabis Research

0


  • Agurell S, Halldin M, Lindgren JE, Ohlsson A, Widman M, Gillespie H, et al. Pharmacokinetics and metabolism of delta-9-tetrahydrocannabinol and other cannabinoids with emphasis on man. Pharmacol Rev. 1986;38(1):21.

    CAS 
    PubMed 

    Google Scholar
     

  • Alvarez L, Colonna R, Kim S, Chen C, Chippure K, Grewal J, et al. Young and under the influence: A systematic literature review of the impact of cannabis on the driving performance of youth. Accid Anal Prev. 2021;151: 105961.

    Article 
    PubMed 

    Google Scholar
     

  • Arkell TR, Lintzeris N, Kevin RC, Ramaekers JG, Vandrey R, Irwin C, et al. Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition. Psychopharmacol. 2019;236(9):2713–24.

  • Arkell TR, Vinckenbosch F, Kevin RC, Theunissen EL, McGregor IS, Ramaekers JG. Effect of Cannabidiol and Delta9-Tetrahydrocannabinol on Driving Performance: A Randomized Clinical Trial. JAMA. 2020;324(21):2177–86.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Asbridge M, Hayden JA, Cartwright JL. Acute cannabis consumption and motor vehicle collision risk: systematic review of observational studies and meta-analysis. BMJ. 2012;344: e536.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ball K, Owsley C, Sloane ME, Roenker DL, Bruni JR. Visual attention problems as a predictor of vehicle crashes in older drivers. Invest Ophthalmol vis Sci. 1993;34(11):3110–23.

    CAS 
    PubMed 

    Google Scholar
     

  • Bosker WM, Kuypers KP, Theunissen EL, Surinx A, Blankespoor RJ, Skopp G, et al. Medicinal Delta(9) -tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests. Addiction. 2012;107(10):1837–44.

    Article 
    PubMed 

    Google Scholar
     

  • Brands B, Mann RE, Wickens CM, Sproule B, Stoduto G, Sayer GS, et al. Acute and residual effects of smoked cannabis: Impact on driving speed and lateral control, heart rate, and self-reported drug effects. Drug Alcohol Depend. 2019;205: 107641.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Brands B, Di Ciano P, Mann RE. Cannabis, Impaired Driving, and Road Safety: An Overview of Key Questions and Issues. Front Psych. 2021;12: 641549.

    Article 

    Google Scholar
     

  • Budney AJ, Novy PL, Hughes JR. Marijuana withdrawal among adults seeking treatment for marijuana dependence. Addiction. 1999;94(9):1311–22.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Budney AJ, Moore BA, Vandrey RG, Hughes JR. The time course and significance of cannabis withdrawal. J Abnorm Psychol. 2003;112(3):393–402.

    Article 
    PubMed 

    Google Scholar
     

  • Chayasirisobhon S. Mechanisms of Action and Pharmacokinetics of Cannabis. Perm J. 2020;25:1–3.

    PubMed 

    Google Scholar
     

  • Daigneault G, Joly P, Frigon J-Y. Executive Functions in the Evaluation of Accident Risk of Older Drivers. J Clin Exp Neuropsychol. 2002;24(2):221–38.

    Article 
    PubMed 

    Google Scholar
     

  • De Raedt R, Ponjaert-Kristoffersen I. The Relationship Between Cognitive/Neuropsychological Factors and Car Driving Performance in Older Adults. J Am Geriatr Soc. 2000;48(12):1664–8.

    Article 
    PubMed 

    Google Scholar
     

  • Di Ciano P, Brands B, Fares A, Wright M, Stoduto G, Byrne P, et al. The Utility of THC Cutoff Levels in Blood and Saliva for Detection of Impaired Driving. Cannabis Cannabinoid Res. 2023;8(3):408–13.

  • Di Ciano P, Matamoros A, Matheson J, Fares A, Hamilton HA, Wickens CM, et al. Effects of therapeutic cannabis on simulated driving: A pilot study. J Concurrent Disord. 2020;2(1).

  • Doroudgar S, Chuang HM, Perry PJ, Thomas K, Bohnert K, Canedo J. Driving performance comparing older versus younger drivers. Traffic Inj Prev. 2017;18(1):41–6.

    Article 
    PubMed 

    Google Scholar
     

  • Downey LA, King R, Papafotiou K, Swann P, Ogden E, Boorman M, et al. The effects of cannabis and alcohol on simulated driving: Influences of dose and experience. Accid Anal Prev. 2013;50:879–86.

    Article 
    PubMed 

    Google Scholar
     

  • Fares A, Wickens CM, Mann RE, Di Ciano P, Wright M, Matheson J, et al. Combined effect of alcohol and cannabis on simulated driving. Psychopharmacol. 2022;239(5):1263–77.

  • Gjerde H, Strand MC. Legal limits for driving under the influence of illicit drugs: Large variations between jurisdictions. Forensic Sci Int Rep. 2023;8.

  • Grotenhermen F. Pharmacokinetics and Pharmacodynamics of Cannabinoids. Clin Pharmacokinet. 2003;42(4):327–60.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Hammond D, Corsetti D, Fataar F, Iraniparast M, Danh Hong D, Burkhalter R. International Cannabis Policy Study- Canada 2022 Summary. 2023.

  • Hartley S, Simon N, Larabi A, Vaugier I, Barbot F, Quera-Salva MA, et al. Effect of Smoked Cannabis on Vigilance and Accident Risk Using Simulated Driving in Occasional and Chronic Users and the Pharmacokinetic-Pharmacodynamic Relationship. Clin Chem. 2019;65(5):684–93.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Hartman RL, Brown TL, Milavetz G, Spurgin A, Pierce RS, Gorelick DA, et al. Cannabis effects on driving longitudinal control with and without alcohol. J Appl Toxicol. 2016;36(11):1418–29.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Health Canada. Canadian Cannabi Survey. 2022. https://www.canada.ca/en/health-canada/services/drugs-medication/cannabis/research-data/canadian-cannabis-survey-2022-summary.html.

  • Hostiuc S, Moldoveanu A, Negoi I, Drima E. The Association of Unfavorable Traffic Events and Cannabis Usage: A Meta-Analysis. Front Pharmacol. 2018;9:99.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lenne MG, Dietze PM, Triggs TJ, Walmsley S, Murphy B, Redman JR. The effects of cannabis and alcohol on simulated arterial driving: Influences of driving experience and task demand. Accid Anal Prev. 2010;42(3):859–66.

    Article 
    PubMed 

    Google Scholar
     

  • Li MC, Brady JE, DiMaggio CJ, Lusardi AR, Tzong KY, Li G. Marijuana use and motor vehicle crashes. Epidemiol Rev. 2012;34(1):65–72.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Marcotte TD, Umlauf A, Grelotti DJ, Sones EG, Sobolesky PM, Smith BE, et al. Driving Performance and Cannabis Users’ Perception of Safety: A Randomized Clinical Trial. JAMA Psychiat. 2022;79(3):201–9.

    Article 

    Google Scholar
     

  • Mauvais-Jarvis F, Berthold HK, Campesi I, Carrero JJ, Dakal S, Franconi F, et al. Sex- and Gender-Based Pharmacological Response to Drugs. Pharmacol Rev. 2021;73(2):730–62.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Miller R, Brown T, Wrobel J, Kosnett MJ, Brooks-Russell A. Influence of cannabis use history on the impact of acute cannabis smoking on simulated driving performance during a distraction task. Traffic Inj Prev. 2022;23(sup1):S1–7.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Newmeyer MN, Swortwood MJ, Abulseoud OA, Huestis MA. Subjective and physiological effects, and expired carbon monoxide concentrations in frequent and occasional cannabis smokers following smoked, vaporized, and oral cannabis administration. Drug Alcohol Depend. 2017a;175:67–76.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Newmeyer MN, Swortwood MJ, Taylor ME, Abulseoud OA, Woodward TH, Huestis MA. Evaluation of divided attention psychophysical task performance and effects on pupil sizes following smoked, vaporized and oral cannabis administration. J Appl Toxicol. 2017b;37(8):922–32.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Newmeyer MN, Swortwood MJ, Andersson M, Abulseoud OA, Scheidweiler KB, Huestis MA. Cannabis Edibles: Blood and Oral Fluid Cannabinoid Pharmacokinetics and Evaluation of Oral Fluid Screening Devices for Predicting Delta(9)-Tetrahydrocannabinol in Blood and Oral Fluid following Cannabis Brownie Administration. Clin Chem. 2017c;63(3):647–62.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Owsley C, Ball K, Sloane ME, Roenker DL, Bruni JR. Visual/cognitive correlates of vehicle accidents in older drivers. Psychol Aging. 1991;6(3):403–15.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Rogeberg O. A meta-analysis of the crash risk of cannabis-positive drivers in culpability studies-Avoiding interpretational bias. Accid Anal Prev. 2019;123:69–78.

    Article 
    PubMed 

    Google Scholar
     

  • Rogeberg O, Elvik R. The effects of cannabis intoxication on motor vehicle collision revisited and revised. Addiction. 2016;111(8):1348–59.

    Article 
    PubMed 

    Google Scholar
     

  • Ronen A, Gershon P, Drobiner H, Rabinovich A, Bar-Hamburger R, Mechoulam R, et al. Effects of THC on driving performance, physiological state and subjective feelings relative to alcohol. Accid Anal Prev. 2008;40(3):926–34.

    Article 
    PubMed 

    Google Scholar
     

  • Sharma P, Murthy P, Bharath M. Chemistry, Metabolism, and Toxicology of Cannabis: Clinical Implications. Iran J Psychiatry. 2012;7:149–56.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Sewell RA, Poling J, Sofuoglu M. The effect of cannabis compared with alcohol on driving. Am J Addict. 2009;18(3):185–93.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Simmons SM, Caird JK, Sterzer F, Asbridge M. The effects of cannabis and alcohol on driving performance and driver behaviour: a systematic review and meta-analysis. Addiction. 2022;117(7):1843–56.

    Article 
    PubMed 

    Google Scholar
     

  • Spindle TR, Cone EJ, Herrmann ES, Mitchell JM, Flegel R, LoDico C, et al. Pharmacokinetics of Cannabis Brownies: A Controlled Examination of Delta9-Tetrahydrocannabinol and Metabolites in Blood and Oral Fluid of Healthy Adult Males and Females. J Anal Toxicol. 2020;44(7):661–71.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Stutts JC, Stewart JR, Martell C. Cognitive test performance and crash risk in an older driver population. Accid Anal Prev. 1998;30(3):337–46.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Vandrey R, Herrmann ES, Mitchell JM, Bigelow GE, Flegel R, LoDico C, et al. Pharmacokinetic Profile of Oral Cannabis in Humans: Blood and Oral Fluid Disposition and Relation to Pharmacodynamic Outcomes. J Anal Toxicol. 2017;41(2):83–99.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Veldstra JL, Bosker WM, de Waard D, Ramaekers JG, Brookhuis KA. Comparing treatment effects of oral THC on simulated and on-the-road driving performance: testing the validity of driving simulator drug research. Psychopharmacol. 2015;232(16):2911–9.

  • Ward NJ DL. Cannabis and driving: a literature review and commentary. DETR; 1999. Report No.: 1468–9138.

  • White MA, Burns NR. The risk of being culpable for or involved in a road crash after using cannabis: A systematic review and meta-analyses. Drug Sci Policy Law. 2021;7.



  • Source link

    This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More